Evidence map›Paper›PMID 41593084›Full record

ArticleNPJ science of food2026

From rosemary and coffee to bioactive nanovesicles: exploring new frontiers in food functional ingredients.

Lorenza d'Adduzio, Gilda Aiello, Umberto Musazzi, Carlotta Bollati, Giorgia Frigerio, Melissa Fanzaga, Maria Silvia Musco, Carmen Lammi

Abstract read
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lorenza d'AdduzioDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Gilda AielloDepartment of Human Science and Quality of Life Promotion, Telematic University San Raffaele, Rome, Italy.
Umberto MusazziDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Carlotta BollatiDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Giorgia FrigerioDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Melissa FanzagaDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Maria Silvia MuscoDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Carmen LammiDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy. carmen.lammi@unimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived vesicles (PDVs) are lipid-membrane structures that enclose proteins, lipids, nucleic acids and metabolites, reflecting the phytochemical profile of their plant source. This study investigated PDVs from Rosmarinus officinalis leaves (RVs) and Coffea arabica powder (CVs), isolated using a patented method. A multidisciplinary and multi-omic approach was employed to characterize their physico-chemical properties, metabolic and lipid profiles, and in vitro biological activities using fibroblasts (BJ-T5A) and myotubes (C2C12). RVs yield showed a higher vesicles concentration, with 1.37 × 10

Identifiers

PMID41593084
PMCPMC12953755

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.