Evidence map›Paper›PMID 41593243›Full record

ArticleNature immunology2026

TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs.

Marine Guivarch, Pierre Meyer, Antoine Braud, Pierre Marschall, Alicia Perrin, Alexis Verdenet, Thien Phong Vu Manh, Pauline Santa, Vanja Sisirak, Ya-Li Zhang and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. IL-17REL disarms inflammation.Nature immunology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Marine Guivarch *Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.ORCID http://orcid.org/0000-0002-7051-9911
Pierre Meyer *Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.ORCID http://orcid.org/0000-0001-9547-7976
Antoine Braud *Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.ORCID http://orcid.org/0000-0001-5207-3357
Pierre MarschallDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Alicia PerrinDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Alexis VerdenetDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Thien Phong Vu ManhAix Marseille University, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Turing Center for Living Systems, Marseille, France.
Pauline SantaCNRS-UMR 5164, ImmunoConcEpT, Bordeaux University, Bordeaux, France.
Vanja SisirakCNRS-UMR 5164, ImmunoConcEpT, Bordeaux University, Bordeaux, France.
Ya-Li ZhangDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Eric FlatterDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Tao YeGenomEast, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Matthieu JungGenomEast, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Marie-Christine BirlingCNRS, INSERM, CELPHEDIA, PHENOMIN, Institut Clinique de la Souris (ICS), Université de Strasbourg, Illkirch, France.ORCID http://orcid.org/0000-0002-3372-8108
Pierre HenerDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Justine SegaudDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.
Beatriz GermanDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France.ORCID http://orcid.org/0009-0004-5105-4583
Dan LipskerDermatology Clinic, Strasbourg University Hospital, Strasbourg, France.
Marc DalodAix Marseille University, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Turing Center for Living Systems, Marseille, France.ORCID http://orcid.org/0000-0002-6436-7966
Mei LiDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104 - INSERM U 1258 - Strasbourg University, Illkirch, France. mei@igbmc.fr.ORCID http://orcid.org/0000-0003-4225-6699

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-10-IDEX-0002Agence Nationale de la Recherche (French National Research Agency) ANR-17-EURE-0023Agence Nationale de la Recherche (French National Research Agency) ANR 20-SFRI-0012Agence Nationale de la Recherche (French National Research Agency) ANR-22-CE14-0023Agence Nationale de la Recherche (French National Research Agency) ANR-23-CE18-0014Fondation ARC pour la Recherche sur le Cancer (ARC Foundation for Cancer Research) n°PJA 20161204687Fondation ARC pour la Recherche sur le Cancer (ARC Foundation for Cancer Research) n°PJA2021060003802Fondation pour la Recherche Médicale (Foundation for Medical Research in France) Equipes FRM 2018Fondation pour la Recherche Médicale (Foundation for Medical Research in France) Equipes FRM 2024Fondation pour la Recherche Médicale (Foundation for Medical Research in France) FDM202306017098Fondation pour la Recherche Médicale (Foundation for Medical Research in France) FDT202404018318
6 · The paper itself

Abstract

Thymic stromal lymphopoietin (TSLP), initially described as a driver of type 2 helper T cell responses, can also act on dendritic cells (DCs) to promote the generation and accumulation of GATA3-expressing effector regulatory T (eT

Indexed as

CytokinesDendritic CellsGATA3 Transcription FactorT-Lymphocytes, RegulatoryAnimalsHumansKeratinocytesMiceMice, Inbred C57BLMice, KnockoutOX40 LigandSkin NeoplasmsThymic Stromal LymphopoietinCytokinesGata3 protein, mouseGATA3 Transcription FactorOX40 LigandThymic Stromal LymphopoietinTnfsf4 protein, mouseTSLP protein, mouse

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.