Evidence map›Paper›PMID 41593296›Full record

ArticleInternational journal of behavioral medicine2026

Healthcare Consumption and Work Absenteeism of Individuals With and Without Persistent Complaints After COVID-19: The Role of Cognitive-Behavioural Factors, Neuropsychological Functioning and Depressive Symptoms.

Anouk Verveen, Eva Camper, Sander C J Verfaillie, Denise Visser, Brent Appelman, Caroline M van Heugten, Janneke Horn, Hanneke E Hulst, Tanja A Kuut, Tessa van der Maaden and 10 more

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Article in International journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

20 authors.

Anouk VerveenAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands. a.verveen@amsterdamumc.nl.
Eva CamperAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands. e.camper@amsterdamumc.nl.
Sander C J VerfaillieAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Denise VisserAmsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Brent AppelmanAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Caroline M van HeugtenMaastricht University, Maastricht, Netherlands.
Janneke HornAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Hanneke E HulstLeiden University, Leiden, Netherlands.
Tanja A KuutAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Tessa van der MaadenNational Institute for Public Health and the Environment (RIVM), Center for Infectious Disease Control, Bilthoven, Netherlands.
Yvonne M G van OsUniversity Medical Center Utrecht, Occupational Health Office, Utrecht, Netherlands.
Maria PrinsPublic Health Service of Amsterdam, Amsterdam, Netherlands.
Johanna M A Visser-MeilyUniversity Medical Center Utrecht, Utrecht, Netherlands.
Michele van VugtAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Cees C van den WijngaardNational Institute for Public Health and the Environment (RIVM), Center for Infectious Disease Control, Bilthoven, Netherlands.
Sandra BrouwerUniversity Medical Center Groningen, Groningen, Netherlands.
Pythia T NieuwkerkAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
Bart van BerckelAmsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Nelleke TolboomUniversity Medical Center Utrecht, Utrecht, Netherlands.
Hans KnoopAmsterdam UMC location University of Amsterdam, Amsterdam, Netherlands. hans.knoop@amsterdamumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare healthcare consumption and work absenteeism of individuals with and without persistent complaints after COVID-19 and determine to what extent cognitive-behavioural factors, neuropsychological functioning and depressive symptoms influence this relationship.

methodIndividuals with (n = 129) and without (n = 96) persistent fatigue (Checklist Individual Strength (CIS) fatigue ≥ 35) and difficulty concentrating (CIS concentration ≥ 18) at least 3 months (IQR 16-28 months) after SARS-CoV-2 infection were included. Using the Treatment Inventory of Costs in Patients, healthcare consumption (number of visits) and work absenteeism (≥ 3 weeks absent from paid work) in the past 3 months were assessed. Mediation analyses were performed to investigate whether the putative factors indeed influence the relationship between persistent complaints and work absenteeism or healthcare consumption.

resultsIndividuals with persistent complaints more often visited a healthcare professional in the past 3 months (3; IQR = 0-11) than participants without persistent complaints (0; IQR = 0-2, p < 0.001). None of the putative factors was associated with healthcare consumption. Work absenteeism (n = 21/85 with paid work) and work disability (n = 27/225) were only reported by participants with persistent complaints, so no mediation analysis could be performed. Within the group with persistent symptoms, worse neuropsychological functioning (attention and executive functioning) and two illness perception subscales were associated with an increased likelihood of work absenteeism.

conclusionThe relationship between reporting persisting symptoms and increased healthcare consumption could not be explained by cognitive-behavioural factors, depressive symptoms or neuropsychological functioning. In participants with persistent complaints, illness perceptions and neuropsychological functioning were associated with work absenteeism.

Indexed as

Healthcare consumptionPASCPost-COVIDSevere fatigueWork absenteeism

Identifiers

PMID41593296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.