ArticleBMC endocrine disorders2026
Serum uric acid and its association with general and abdominal obesity and elevated blood pressure among young adults in Sylhet division, Bangladesh.
Article in BMC endocrine disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Immunometabolic Dysregulation in Preeclampsia: Emerging Roles of Inflammation, Insulin Resistance, Uric Acid, and the Gut Microbiome.Mediators of inflammation · 2026Review
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Abstract
backgroundObesity and elevated blood pressure at a young age can lead to serious health complications later in life. The prevalence of both conditions is rising rapidly in both developing and developed countries. However, limited information is available regarding the association between serum uric acid (SUA), obesity, and elevated blood pressure in young adults. Therefore, this study aimed to investigate the relationships among SUA, general and abdominal obesity, and elevated blood pressure in Bangladeshi young adults.
methodsIn this cross-sectional study, blood samples were collected from 461 young adults (281 males and 180 females) aged 18–28 years. Levels of SUA, fasting blood glucose (FBG), and lipid profile parameters (TG, TC, LDL-C, and HDL-C) were measured using standard colorimetric methods. Participants were divided into four quartiles based on SUA concentrations. Multiple logistic regression analyses were performed to evaluate the associations of SUA with both types of obesity and elevated blood pressure.
resultsThe overall prevalence of hyperuricemia was 25.4%, with 28.5% in males and 20.6% in females. The mean SUA level was significantly higher in males (6.7 ± 1.5 mg/dL) than in females (5.3 ± 1.3 mg/dL) (p < 0.01). The prevalence of general obesity increased significantly across the SUA quartiles (7.7%, 17.3%, 19.2%, and 55.8%, respectively, p < 0.001). An increasing trend in abdominal obesity prevalence was also observed across the SUA quartiles, except quartile 3 (22.6%, 25.0%, 19.6%, and 32.7%, respectively, p < 0.05). Similarly, a rising trend in elevated blood pressure prevalence was found with higher SUA across the SUA quartiles (17.8%, 24.1%, 26.6%, and 31.5%, respectively, p < 0.001). Males had a comparatively higher prevalence of both types of obesity and elevated blood pressure than their female counterparts. SUA levels were significantly and positively correlated with SBP, DBP, BMI, WC, and HC (p < 0.01 for all). In the regression models, SUA remained positively and significantly associated with both general and abdominal obesity, as well as elevated blood pressure, after adjustment for confounders.
conclusionsThe findings indicate that the prevalence of obesity and elevated blood pressure increases with higher SUA levels. Elevated SUA was positively associated with both general and abdominal obesity as well as elevated blood pressure in this population. Effective management of SUA, along with controlling obesity and blood pressure, may help prevent related health complications in young adults. CLINICAL TRIAL NUMBER: Not applicable.
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