Evidence map›Paper›PMID 41594648›Full record

ArticleBiomolecules2026

Systemic Interplay of BDNF and Serotonin Pathways Defines Behavioral and Molecular Responses to Midbrain 5-HT7 Overexpression and Chronic Ethanol Consumption.

Alexander Rodnyy, Alina Oreshko, Dmitry Eremin, Vladimir Naumenko, Darya Bazovkina

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander RodnyyFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.ORCID 0000-0001-5739-4176
Alina OreshkoFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.ORCID 0009-0008-0742-5905
Dmitry EreminFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.ORCID 0009-0005-8261-1183
Vladimir NaumenkoFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.ORCID 0000-0001-7196-4729
Darya BazovkinaFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.ORCID 0000-0001-5786-7965

Funding

Russian Science Foundation No. 25-75-00087
6 · The paper itself

Abstract

Chronic ethanol exposure and genetic factors interact to drive neuroadaptations in alcohol use disorders (AUD). However, the system-level coordination of molecular responses across brain regions remains unclear. The 5-HT system and BDNF are key regulators of neuroplasticity in alcoholism. The 5-HT

Indexed as

Brain-Derived Neurotrophic FactorCentral Nervous System DepressantsEthanolMesencephalonSerotoninAlcohol DrinkingAnimalsBehavior, AnimalMaleMiceMice, Inbred C57BLOpen Field TestBrain-Derived Neurotrophic FactorCentral Nervous System DepressantsEthanolSerotonin5-HT7 receptorAAV-mediated overexpressionbrain 5-HT systemBrain-derived neurotrophic factor (BDNF)chronic alcoholizationmale mice

Identifiers

PMID41594648
PMCPMC12838814

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.