Evidence map›Paper›PMID 41594678›Full record

ReviewBiomolecules2026

Advances in Cytokines and Inflammatory Mechanisms in the Pathogenesis of Interstitial Cystitis/Bladder Pain Syndrome.

Yulin Xiao, Donglin Zhu, Xiangfu Zhou

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yulin XiaoDepartment of Urology, The Third Affiliated Hospital of Sun Yat-sen University, 600 W Tianhe Rd., Guangzhou 510630, China.
Donglin ZhuDepartment of Urology, The Third Affiliated Hospital of Sun Yat-sen University, 600 W Tianhe Rd., Guangzhou 510630, China.ORCID 0000-0001-8661-1977
Xiangfu ZhouDepartment of Urology, The Third Affiliated Hospital of Sun Yat-sen University, 600 W Tianhe Rd., Guangzhou 510630, China.

Funding

the Natural Science Foundation of Guangdong Province 2024A1515010461the Open Research Funds from Affiliated Qingyuan Hospital, Guangzhou Medical University, Qingyuan People's Hospital 202301323
6 · The paper itself

Abstract

Bladder discomfort, urgency, and frequency of urination are the hallmarks of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic illness. Although the precise etiology remains unclear, numerous clinical investigations have established inflammation as a pivotal factor in its pathogenesis, encompassing uroepithelial damage, mast cell activation, and neuroinflammatory responses. This review delineates the pathological features and classification of IC/BPS, emphasizing the contribution of inflammatory mechanisms and the involvement of cytokines as key mediators in disease progression. The insights presented aim to guide the advancement of innovative treatment approaches.

Indexed as

Cystitis, InterstitialCytokinesInflammationAnimalsHumansMast CellsUrinary BladderCytokinescytokinesinflammatory mechanismsinterstitial cystitis/bladder pain syndrome

Identifiers

PMID41594678
PMCPMC12839389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.