Evidence map›Paper›PMID 41594898›Full record

ArticleBiology2026

Dietary Methionine Supplementation Improves Rainbow Trout (

Mariana Vaz, Gonçalo Espregueira Themudo, Inês Carvalho, Felipe Bolgenhagen Schöninger, Carolina Tafalla, Patricia Díaz-Rosales, Benjamín Costas, Marina Machado

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana VazCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0001-6064-0227
Gonçalo Espregueira ThemudoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0002-5019-9439
Inês CarvalhoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0001-9309-2650
Felipe Bolgenhagen SchöningerCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0003-3890-0330
Carolina TafallaFish Immunology and Pathology Group, Biotechnology Department, National Institute for Agricultural and Food Research and Technology (INIA), Spanish National Research Council (CSIC), Carretera de La Coruña km 7.5, 28040 Madrid, Spain.ORCID 0000-0002-0860-2976
Patricia Díaz-RosalesFish Immunology and Pathology Group, Biotechnology Department, National Institute for Agricultural and Food Research and Technology (INIA), Spanish National Research Council (CSIC), Carretera de La Coruña km 7.5, 28040 Madrid, Spain.
Benjamín CostasCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0003-3758-0849
Marina MachadoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Porto, Portugal.ORCID 0000-0001-7718-5021

Funding

This research was funded by the European Union's Horizon Europe research and innovation programme (GA No.101079467 project GRINNAQUA - GReen INNovation strategies for animal health management: towards sustainable AQUAculture) 101079467
6 · The paper itself

Abstract

Several studies have demonstrated that methionine supplementation in fish diets enhances immune status, inflammatory response, and resistance to bacterial infections by modulating for DNA methylation, aminopropylation, and transsulfuration pathways. However, the immunomodulatory effects of methionine in viral infections remain unexplored. This study aimed to evaluate the effect of methionine supplementation on immune modulation and resistance to the viral haemorrhagic septicaemia virus (VHSV) in rainbow trout (

Indexed as

amino acidsimmune responseimmunomodulationinflammationtranscriptomics

Identifiers

PMID41594898
PMCPMC12837368

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.