Evidence map›Paper›PMID 41595224›Full record

ReviewCancers2026

Predicting the Unpredictable: AI-Driven Prognosis in Pancreatic Neuroendocrine Neoplasms.

Elettra Merola, Emanuela Pirino, Stefano Marcucci, Franca Chierichetti, Andrea Michielan, Laura Bernardoni, Armando Gabbrielli, Maria Pina Dore, Giuseppe Fanciulli, Alberto Brolese

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elettra MerolaDipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.ORCID 0000-0001-9553-7684
Emanuela PirinoDipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.
Stefano MarcucciHepato-Pancreato-Biliary (HPB) Unit, Department of General Surgery, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0001-9144-9038
Franca ChierichettiDepartment of Nuclear Medicine, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0002-1898-4736
Andrea MichielanGastroenterology and Digestive Endoscopy Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0003-1353-0935
Laura BernardoniGastroenterology and Digestive Endoscopy Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0002-1712-4582
Armando GabbrielliGastroenterology and Digestive Endoscopy Unit, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0001-5875-7952
Maria Pina DoreDipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.ORCID 0000-0001-7305-3531
Giuseppe FanciulliDipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.ORCID 0000-0002-8367-5649
Alberto BroleseHepato-Pancreato-Biliary (HPB) Unit, Department of General Surgery, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), 38122 Trento, Italy.ORCID 0000-0002-6362-9055

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical management of Pancreatic Neuroendocrine Neoplasms (Pan-NENs) is complicated by the disease's intrinsic variability, which creates significant hurdles for accurate risk profiling and the standardization of treatment protocols. Recently, Artificial Intelligence (AI) has offered a promising avenue to address these challenges. By integrating and processing high-dimensional multimodal datasets (encompassing clinical history, radiomics, and pathology), these computational tools can refine survival forecasts and support the development of personalized medicine. However, the transition from experimental success to routine clinical use is currently obstructed by reliance on limited, retrospective cohorts that lack external validation, alongside unresolved concerns regarding algorithmic transparency and ethical governance. This review evaluates the current landscape of AI-driven prognostic modeling for Pan-NENs and critically examines the pathway towards their reliable integration into clinical practice.

Indexed as

artificial intelligenceclinical outcomespancreatic neuroendocrine neoplasmsprognostic modelssurvival

Identifiers

PMID41595224
PMCPMC12839224

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.