Evidence mapPaperPMID 41595294Full record

ArticleHealthcare (Basel, Switzerland)2026

Psychological Distress and Health-Related Quality of Life in Romanian Adults with Diabetes Mellitus: A Cross-Sectional Study.

Lucia Bubulac, Carmen Gabriela Dobjanschi, Mirela Zivari, Constantin Erena, Viorica Tudor, Arsenie Dan Spînu, Gabriela Cornelia Muşat, Claudia Florina Bogdan-Andreescu, Emin Cadar, Cristina-Crenguța Albu

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Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

10 authors.

Lucia BubulacDepartment of Family Medicine, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-1541-9870
Carmen Gabriela DobjanschiDiscipline of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Mirela ZivariDepartment of Psychology and Educational Sciences, Faculty of Psychology, Ecological University of Bucharest, 061341 Bucharest, Romania.
Constantin ErenaInternal Medicine Department, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0009-0008-5700-7672
Viorica TudorIntegrated Outpatient Department, "Prof. Dr. Agrippa Ionescu" Clinical Emergency Hospital, 011356 Bucharest, Romania.
Arsenie Dan SpînuDepartment 3, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Gabriela Cornelia MuşatDepartment II, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-6731-3341
Claudia Florina Bogdan-AndreescuDepartment of Speciality Disciplines, "Titu Maiorescu" University, 031593 Bucharest, Romania.ORCID 0000-0001-5965-893X
Emin CadarFaculty of Pharmacy, "Ovidius" University, 900470 Constanța, Romania.ORCID 0000-0002-0085-2081
Cristina-Crenguța AlbuDepartment of Genetics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-9783-149X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsychological distress is increasingly recognized as an important determinant of health-related quality of life (HRQoL) in adults with diabetes mellitus (DM). However, data quantifying this burden in Eastern European populations remains limited.

objectivesThis study aimed to assess psychological distress-defined as anxiety, depressive symptoms, or perceived stress-and HRQoL among Romanian adults with DM compared with healthy controls, and to explore potential differences between diabetes subtypes.

methodsA cross-sectional study was conducted, including 400 adults (201 with DM and 199 healthy controls). Psychological distress was evaluated using the State-Trait Anxiety Inventory (STAI-Y1, STAI-Y2), Beck Depression Inventory (BDI), and Holmes-Rahe Stress Scale, while HRQoL was assessed using the EQ-5D Visual Analogue Scale. Group comparisons were performed using appropriate parametric or non-parametric tests, with additional multivariable analyses adjusting for age, sex, and body mass index.

resultsAdults with diabetes exhibited significantly higher levels of anxiety, depressive symptoms, and perceived stress, and lower HRQoL, compared with controls (all

conclusionsPsychological distress is highly prevalent among Romanian adults with DM and is associated with poorer self-perceived health-related quality of life. The results support the relevance of incorporating systematic psychosocial assessment into routine diabetes care.

Indexed as

anxietychronic diseasedepressiondiabetes mellitusEQ-5Dhealth-related quality of lifeperceived stresspsychological burden

Identifiers

PMID41595294
PMCPMC12841257

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