Evidence map›Paper›PMID 41595605›Full record

ReviewBiomedicines2025

Coenzyme A in Brain Biology and Neurodegeneration.

Dejun Zhang, Charlie Brett, Jason Cho, Tammaryn Lashley, Ivan Gout

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Molecular subtyping-guided precision therapy for ESCC: biomarker-driven strategies and clinical translation pathways.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dejun ZhangDepartment of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.
Charlie BrettDepartment of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.
Jason ChoDepartment of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.ORCID 0009-0004-8323-5354
Tammaryn LashleyDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.ORCID 0000-0001-7389-0348
Ivan GoutDepartment of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.ORCID 0000-0001-9179-8393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coenzyme A (CoA) biology has been extensively studied in health and disease due to the central role of CoA in numerous metabolic and signalling processes. CoA is essential for all living organisms, and its biosynthesis and homeostasis are tightly regulated by nutrient availability, mitogenic stimuli, and stress signals. Disruptions in CoA biosynthesis, caused by inborn mutations in genes encoding enzymes of the CoA biosynthetic pathway (such as

Indexed as

Coenzyme Aneurodegenerationredox regulation

Identifiers

PMID41595605
PMCPMC12839256

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.