Evidence map›Paper›PMID 41595991›Full record

ArticleBioengineering (Basel, Switzerland)2026

Immersive Virtual Reality for Stroke Rehabilitation: Linking Clinical and Digital Measures of Motor Recovery-A Pilot Study.

Livia-Alexandra Ion, Miruna Ioana Săndulescu, Claudia-Gabriela Potcovaru, Daniela Poenaru, Andrei Doru Comișel, Ștefan Ștefureac, Andrei Cristian Lambru, Alin Moldoveanu, Ana Magdalena Anghel, Delia Cinteză

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Livia-Alexandra IonNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0009-0002-9170-5016
Miruna Ioana SăndulescuNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.
Claudia-Gabriela PotcovaruNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0009-0003-5801-5416
Daniela PoenaruNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0000-0003-4135-5695
Andrei Doru ComișelNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0009-0004-7946-7734
Ștefan ȘtefureacNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0009-0007-9719-1788
Andrei Cristian LambruComputers Department, Faculty of Automatic Control and Computers, National University of Science and Technology Politehnica Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-3168-9969
Alin MoldoveanuComputers Department, Faculty of Automatic Control and Computers, National University of Science and Technology Politehnica Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-1368-7249
Ana Magdalena AnghelAutomatic Control and Applied Informatics Department, Faculty of Automatic Control and Computers, National University of Science and Technology Politehnica Bucharest, 060042 Bucharest, Romania.ORCID 0009-0007-3045-0239
Delia CintezăNational Institute of Rehabilitation, Physical Medicine and Balneoclimatology, 030079 Bucharest, Romania.ORCID 0000-0001-6216-6688

Funding

Ministerul Cercetării și Inovării PN-IV-P7-7.1-PTE-2024-0764
6 · The paper itself

Abstract

backgroundImmersive virtual reality (VR) has emerged as a promising tool to enhance neuroplasticity, motivation, and engagement during post-stroke motor rehabilitation. However, evidence on its feasibility and data-driven integration into clinical practice remains limited.

objectiveThis pilot study aimed to evaluate the feasibility, usability, and short-term motor outcomes of an immersive VR-assisted rehabilitation program using the Travee-VR system.

methodsFourteen adults with post-stroke upper-limb paresis completed a 10-day hybrid rehabilitation program combining conventional therapy with immersive VR sessions. Feasibility and tolerability were assessed through adherence, adverse events, the System Usability Scale (SUS), and the Simulator Sickness Questionnaire (SSQ). Motor outcomes included active and passive range of motion (AROM, PROM) and a derived GAP index (PROM-AROM). Correlations between clinical changes and in-game performance metrics were explored to identify potential digital performance metrics of recovery.

resultsAll participants completed the program without adverse events. Usability was rated as high (mean SUS = 79 ± 11.3), and cybersickness remained mild (SSQ < 40). Significant improvements were observed in shoulder abduction (+7.3°,

conclusionsThe Travee-VR system proved feasible, well tolerated, and associated with measurable short-term improvements in upper-limb function. By linking clinical outcomes with real-time kinematic data, this study supports the role of immersive, feedback-driven VR as a catalyst for data-informed neuroplastic recovery. These results lay the groundwork for adaptive, clinic-to-home rehabilitation models integrating clinical and exploratory digital performance metrics.

Indexed as

data-driven rehabilitationfeasibility studyimmersive virtual realitymotor recoveryneuroplasticitystroke rehabilitationusability

Identifiers

PMID41595991
PMCPMC12837790

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.