ArticleBioengineering (Basel, Switzerland)2026
Macromolecular Proton Fraction Reveals Divergent White Matter Myelination in Bipolar Disorder and Unipolar Recurrent Depression.
Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Divergent Myelination or Divergent Trajectories? Insights from MPF Mapping in Bipolar Disorder and Recurrent Depressive Disorder.Bioengineering (Basel, Switzerland) · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Recurrent depressive disorder (RDD) and bipolar disorder (BD) are the most common affective disorders worldwide. However, the pathogenesis of these disorders remains far from understood. Macromolecular proton fraction (MPF) mapping is a sensitive and specific quantitative MRI method for the assessment of brain tissue myelination, but its clinical value for affective disorders remains unknown. This cross-sectional study employed fast MPF mapping on a 1.5 T MRI scanner using the single-point synthetic reference method to investigate myelin abnormalities in white matter of RDD and BD patients. ANOVA revealed a significant main effect of the group (RDD vs. BD vs. two age-matched control groups; F (3.76) = 7.42,
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Registered trials
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