ReviewAntioxidants (Basel, Switzerland)2026
Emerging Therapeutic Strategies for Nrf2-Associated Skin Disorders: From Photoaging to Autoimmunity.
Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Rutin as a multi-target anti-inflammatory phytochemical in arthritic disorders: pharmacological mechanisms and therapeutic potential.Inflammopharmacology · 2026Review
- Sulforaphane in Cutaneous Disorders and Skin Injury: Mechanisms, Evidence, and Clinical Perspectives.Nutrients · 2026Review
- Biological Activity of Hops (Nutrients · 2026Review
- Hydrolyzed corn starch with maltotetraose for skin defense through NRF2 pathway activation in human keratinocytes.PloS one · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of the cellular antioxidant response, modulating redox homeostasis, detoxification, and cytoprotective pathways. Impaired Nrf2 signaling has been associated with a wide range of cutaneous pathologies, including photoaging, autoimmune disorders, and inflammation. In this review, we highlight roles of Nrf2 in the physiological and pathological mechanisms underlying oxidative stress, autoimmunity-associated skin damage, and fibrotic diseases, with a particular emphasis on photoaging, psoriasis, vitiligo, and autoimmune-associated skin fibrosis. Furthermore, we elucidate several natural bioactive compounds, their therapeutic applications, and delivery platforms for mitigating oxidative stress-mediated skin damage through the modulation of Nrf2 signaling, aiming to translate basic insights into clinical interventions for oxidative stress-driven skin disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.