Evidence map›Paper›PMID 41596198›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Baicalin Alleviates Chronic Restraint Stress-Induced Depression-like Behavior by Suppressing ROS/H

Yu-Ning Teng, Tien-Wei Hsu, Wei-Hao Peng, Cheng-Chun Wu, Tian-Huei Chu, Yung-Kuo Lee, Ming Tatt Lee, Yu-Cheng Ho

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Ning TengSchool of Pharmacy, China Medical University, Taichung City 406040, Taiwan.ORCID 0000-0003-4364-7720
Tien-Wei HsuSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung 824005, Taiwan.
Wei-Hao PengSchool of Medicine, National Tsing Hua University, Hsinchu 300044, Taiwan.ORCID 0000-0002-7524-1218
Cheng-Chun WuSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung 824005, Taiwan.ORCID 0000-0002-7084-9208
Tian-Huei ChuMedical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung 802301, Taiwan.
Yung-Kuo LeeMedical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung 802301, Taiwan.ORCID 0000-0003-1638-8049
Ming Tatt LeeOffice of Postgraduate Studies, UCSI University, Kuala Lumpur 56000, Malaysia.ORCID 0000-0003-3957-2439
Yu-Cheng HoSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung 824005, Taiwan.

Funding

China Medical University CMU114-MF-64E-Da Hospital EDAHS113046E-Da Hospital EDAHS114027National Science and Technology Council, Taipei, Taiwan MOST 111-2320-B-214-002-MY3National Science and Technology Council, Taipei, Taiwan NSTC 112-2320-B-039-063-MY3National Science and Technology Council, Taipei, Taiwan NSTC 112-2320-B-214-003-MY3National Science and Technology Council, Taipei, Taiwan NSTC 114-2320-B-214-002UCSI University Research Excellence and Innovation Grant REIG-OPS-2025/043
6 · The paper itself

Abstract

Major depressive disorder (MDD) is a leading cause of global morbidity and mortality. Although pharmacological treatments are widely used, their effects are often limited, and nearly half of patients show resistance to current antidepressants, including those unresponsive to all available therapies. These challenges highlight the need to better understand the neurobiological mechanisms driving MDD and to develop novel therapeutic strategies, especially those involving natural compounds with multitarget actions. Baicalin, a bioactive flavonoid from

Indexed as

baicalinchronic stressdepressionhippocampuslong-term potentiationROS

Identifiers

PMID41596198
PMCPMC12837477

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.