Evidence map›Paper›PMID 41596308›Full record

ArticleInternational journal of molecular sciences2026

Targeted Therapy for a Rare

Cosimo Barbato, Vito A Lasorsa, Francesco Grimaldi, Santa Errichiello, Ida Pisano, Maurizio Capuozzo, Mariangela Capone, Viviana Izzo, Fabrizio Quarantelli, Alessandra Potenza and 10 more

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in oncology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Cosimo BarbatoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0009-0004-9079-1455
Vito A LasorsaCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0000-0002-9552-7192
Francesco GrimaldiHematology Section, Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80138 Naples, Italy.
Santa ErrichielloCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Ida PisanoUOSD Medical Genetics Laboratory, ASL Napoli 1 Centro, 80141 Naples, Italy.
Maurizio CapuozzoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Mariangela CaponeCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Viviana IzzoUOC of Clinical Pharmacology, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.ORCID 0000-0001-6066-7569
Fabrizio QuarantelliCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0000-0003-0744-5734
Alessandra PotenzaCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0009-0001-9233-2998
Roberta ViscontiCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Alessandra GaldieroCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Angelo ZannitiCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Ciro Del PreteCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Teresa FemianoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Giuseppina EspositoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.
Novella PuglieseHematology Section, Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80138 Naples, Italy.ORCID 0000-0002-2714-5109
Roberta RussoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0000-0002-3624-7721
Mario CapassoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0000-0003-3306-1259
Barbara IzzoCEINGE Biotecnologie Avanzate Franco Salvatore, 80145 Naples, Italy.ORCID 0000-0002-7021-0367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloproliferative neoplasms (MPNs) are a heterogeneous group of diseases originating from hematopoietic stem cell transformation, characterized by the clonal proliferation of hematopoietic progenitors. A specific subset includes myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase (TK) gene fusions, particularly involving

Indexed as

Gene RearrangementMyeloproliferative DisordersProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor betaChromosomes, Human, Pair 5HumansMaleMolecular Targeted TherapyOncogene Proteins, FusionYoung AdultOncogene Proteins, FusionPDGFRB protein, humanProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor betaCCDC88C genecytogeneticsimatinibmyeloproliferative neoplasms (MPNs)PDGFRB geneRNA sequencing (RNAseq)whole genome sequencing (WGS)

Identifiers

PMID41596308
PMCPMC12841148

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.