Evidence mapPaperPMID 41596358Full record

ArticleInternational journal of molecular sciences2026

Differential Oxidative Stress Profiles in Circulating and Peritumoral Adipose Tissue Across Stages of Colorectal Cancer.

Somchai Ruangwannasak, Sittichai Khamsai, Poungrat Pakdeechote, Putcharawipa Maneesai, Parichat Prachaney, Wilaiwan Mothong, Chalerm Eurboonyanun

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Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Somchai RuangwannasakDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Sittichai KhamsaiDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-6052-5621
Poungrat PakdeechoteDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0001-8114-5954
Putcharawipa ManeesaiDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-0889-6211
Parichat PrachaneyDepartment of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Wilaiwan MothongDepartment of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Chalerm EurboonyanunDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-8103-1364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study intends to assess oxidative stress markers and endogenous enzymes in plasma and peritumoral adipose tissues (PATs) obtained from normal subjects and patients with stages I-IV colorectal cancer (CRC). 63 participants were recruited, including 23 patients with colorectal cancer and 40 healthy subjects. CRC patients had increased circulating malondialdehyde (MDA) and protein carbonyl concentrations, as well as reduced superoxide dismutase (SOD) and catalase activities, compared to normal volunteers. (

Indexed as

Adipose TissueColorectal NeoplasmsOxidative StressAgedCatalaseFemaleHeme Oxygenase-1HumansMaleMalondialdehydeMiddle AgedNeoplasm StagingNF-E2-Related Factor 2Superoxide DismutaseSuperoxidesCatalaseHeme Oxygenase-1HMOX1 protein, humanMalondialdehydeNFE2L2 protein, humanNF-E2-Related Factor 2Superoxide DismutaseSuperoxidescatalase activitycolorectal cancermalondialdehydeprotein carbonylsuperoxide dismutase activity

Identifiers

PMID41596358
PMCPMC12841512

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.