Iatrogenic Hypoglycemia in Type 2 Diabetes Affects Endothelial Proteins Involved in Cardiovascular Dysfunction.

Edwina Brennan, Abu Saleh Md Moin, Thozhukat Sathyapalan, Laura Dempsey, Stephen L Atkin, Alexandra E Butler

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edwina BrennanSchool of Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0003-0183-4683

Abu Saleh Md MoinSchool of Postgraduate Studies and Research, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5342-2501

Thozhukat SathyapalanAcademic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Hull HU6 7RX, UK.ORCID 0000-0003-3544-2231

Laura DempseyData Science Centre, School of Population Health, Royal College of Surgeons in Ireland, D02 DH60 Dublin, Ireland.

Stephen L AtkinSchool of Postgraduate Studies and Research, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5887-7257

Alexandra E ButlerSchool of Postgraduate Studies and Research, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5762-3917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoglycemia is associated with cardiovascular events reflected by platelet abnormalities. We hypothesized that sequential endothelial changes may occur during hypoglycemia that may enhance cardiovascular risk. In type 2 diabetes (T2D) (

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2HypoglycemiaAgedCadherinsEndothelium, VascularE-SelectinFemaleHumansInsulinMaleMiddle AgedPlasminogen Activator Inhibitor 1ProteomicsP-SelectinCadherinsE-SelectinInsulinPlasminogen Activator Inhibitor 1P-Selectinendothelial proteinshypoglycemiaintercellular adhesion molecule 3plasminogen activator inhibitor-1selectinsT2Dtype 2 diabetes

Identifiers

PMID41596469

DOI10.3390/ijms27020822

PMCPMC12841412

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.