Evidence map›Paper›PMID 41597006›Full record

ArticleFoods (Basel, Switzerland)2026

Untargeted Metabolomics Reveals Raw Material Geographic Origin as a Key Factor Shaping the Quality of Ginger-Derived Exosome-like Nanovesicles.

Zhuo Chen, Xinyi Zhang, Liuliu Luo, Qiang Liu, Pingduo Chen, Jinnian Peng, Fangfang Min, Yunpeng Shen, Jingjing Li, Yongning Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhuo ChenState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Xinyi ZhangState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Liuliu LuoState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Qiang LiuSino-German Joint Research Institute, Nanchang University, Nanchang 330047, China.
Pingduo ChenState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Jinnian PengSchool of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Fangfang MinState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Yunpeng ShenState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Jingjing LiState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.
Yongning WuNHC Key Lab of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment (CFSA), Beijing 100022, China.ORCID 0000-0001-6430-1302
Hongbing ChenState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China.ORCID 0000-0002-4845-383X

Funding

Shandong province Key R&D Program in China 2022TZXD0026
6 · The paper itself

Abstract

A major challenge for food-derived bio-nanomaterials is achieving consistent and predictable functional properties to ensure their quality. Ginger-derived exosome-like nanovesicles (GELNs) serve as an ideal model for this challenge, yet the impact of ginger geographical origin on GELNs remains unknown. This study aims to establish a quality control framework for food-derived bio-nanomaterials. GELNs were comprehensively analyzed. Untargeted metabolomics identified differential metabolites, which were then screened for correlation with antioxidant capacity. Machine learning was employed to pinpoint potential quality markers, and Kyoto Encyclopedia of Genes and Genomes enrichment analysis highlighted key metabolic pathways. Significant variations in physicochemical properties and bioactivities were observed. We identified 190 differential compounds and established a panel of 6 potential quality markers. Enrichment analysis revealed eight key pathways, with "microbial metabolism in diverse environments" and "galactose metabolism" being most prominent. The quality marker mollicellin I (derived from

Indexed as

antioxidant activityfood-derived nanomaterialGELNsgingeruntargeted metabolomics

Identifiers

PMID41597006
PMCPMC12841063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.