Evidence map›Paper›PMID 41597470›Full record

Trial reportMedicina (Kaunas, Lithuania)2026

Real-World Transition to a Preservative-Free Fixed Combination of Dorzolamide/Timolol: Impact on the Ocular Surface Microenvironment, Safety, Tolerability, and Efficacy.

Ana Sanseau, Arturo Burchakchi, Fernando Cataldi, Héctor Fontana, Alejo Peyret, Giselle Rodríguez, Ailín Fantacone, María Silvia Passerini, Javier F Casiraghi

Abstract readClinical Trial, Phase IVMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana SanseauHospital J. M. Ramos Mejía, Ciudad Autónoma de Buenos Aires C1221ADC, Argentina.ORCID 0000-0001-8072-2916
Arturo BurchakchiHospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires C1199ABB, Argentina.ORCID 0000-0003-4118-9957
Fernando CataldiClínica de Ojos Dr. Nano, Buenos Aires B1636CSS, Argentina.
Héctor FontanaHospital Santa Lucía, Ciudad Autónoma de Buenos Aires C1232AAC, Argentina.
Alejo PeyretHospital Durand, Ciudad Autónoma de Buenos Aires C1405DCS, Argentina.
Giselle RodríguezLaboratorios POEN S.A.U., Ciudad Autónoma de Buenos Aires C1407BDR, Argentina.ORCID 0009-0002-2614-7708
Ailín FantaconeLaboratorios POEN S.A.U., Ciudad Autónoma de Buenos Aires C1407BDR, Argentina.
María Silvia PasseriniLaboratorios POEN S.A.U., Ciudad Autónoma de Buenos Aires C1407BDR, Argentina.ORCID 0000-0001-5148-9078
Javier F CasiraghiHospital de Clínicas, Ciudad Autónoma de Buenos Aires C1120AAR, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dry Eye SyndromesSulfonamidesThiophenesTimololAdultAgedDrug CombinationsFemaleHumansIntraocular PressureMaleMiddle AgedOphthalmic SolutionsPatient SatisfactionPreservatives, PharmaceuticalProspective Studiesdorzolamide-timolol combinationDrug CombinationsOphthalmic SolutionsPreservatives, PharmaceuticalSulfonamidesThiophenesTimololdorzolamideglaucomaocular surface diseaseocular surface microenvironmentpreservative-freetimolol

Identifiers

PMID41597470
PMCPMC12843284

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.