Evidence map›Paper›PMID 41597602›Full record

ArticleMicroorganisms2025

Longitudinal Analysis of Vulvovaginal Bacteriome Following Use of Water- and Silicone-Based Personal Lubricants: Stability, Spatial Specificity, and Clinical Implications.

Jose A Freixas-Coutin, Jin Seo, Lingyao Su, Sarah Hood

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jose A Freixas-CoutinReckitt Health US LLC, 1 Philips Pkwy, Montvale, NJ 07645, USA.ORCID 0000-0001-6324-3374
Jin SeoReckitt Health US LLC, 1 Philips Pkwy, Montvale, NJ 07645, USA.ORCID 0000-0002-0134-1937
Lingyao SuRB (Shanghai) Technology Co., Ltd., Shanghai 200030, China.
Sarah HoodReckitt Benckiser Healthcare Ltd., Hull HU8 7DS, UK.

Funding

Reckitt Benckiser (United Kingdom) NA
6 · The paper itself

Abstract

The vulvovaginal microbiome is a complex and dynamic ecosystem of microorganisms. The potential effects of common personal lubricants on its balance, which have implications for reproductive health, are still unknown. This study longitudinally assessed the impact of two commercially available lubricants on the composition and stability of the vaginal and vulvar bacteriome. Paired vaginal and vulvar swabs were collected at baseline and after repeated lubricant use, and the bacteriome was assessed using 16S rRNA gene amplicon sequencing. Alpha and beta diversity were assessed using Shannon entropy and Bray-Curtis dissimilarity, respectively. The results showed that the vaginal bacteriome was dominated by

Indexed as

16S rRNA genemenopausepersonal lubricantsvaginal drynessvulvovaginal bacteriome

Identifiers

PMID41597602
PMCPMC12844435

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.