Evidence map›Paper›PMID 41597643›Full record

ArticleMicroorganisms2026

Microvesicle Profiles in Patients with HIV, HBV, and HCV Infections: An Exploratory Pilot Study.

Georgios Dryllis, Sotirios P Fortis, Nikolaos Martsoukos, Vasiliki Pantazatou, Evgenia Spyropoulou, Despoina Pontikaki, Christelos Kapatais, Nikolaos Tsakalis, Andrianna Konstantelou, Eleni Myrto Trifylli and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Georgios DryllisLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Sotirios P FortisLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Nikolaos MartsoukosLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Vasiliki PantazatouLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Evgenia SpyropoulouLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Despoina PontikakiGeneral Hospital of West Attica "Agia Varvara'', 12351 Athens, Greece.
Christelos KapataisGeneral Hospital of West Attica "Agia Varvara'', 12351 Athens, Greece.ORCID 0009-0003-5402-3160
Nikolaos TsakalisGeneral Hospital of West Attica "Agia Varvara'', 12351 Athens, Greece.
Andrianna Konstantelou1st Department of Internal Medicine, General Hospital of Nikea "Agios Panteleimon", 18454 Piraeus, Greece.
Eleni Myrto TrifylliGastrointestinal-Liver Unit, The 2nd Department of Internal Medicine, National and Kapodistrian University of Athens, General Hospital of Athens "Hippocratio", 11521 Athens, Greece.ORCID 0000-0002-0080-9032
Andreas G TsantesLaboratory of Haematology and Blood Bank Unit, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0002-3695-0759
Effie G PapageorgiouLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.
Serena ValsamiHematology Laboratory and Blood Bank, Aretaieion Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-1034-6510
Andreas KapataisGeneral Hospital of West Attica "Agia Varvara'', 12351 Athens, Greece.
Olga Kosmopoulou1st Department of Internal Medicine, General Hospital of Nikea "Agios Panteleimon", 18454 Piraeus, Greece.
Anastasios G KriebardisLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica (UniWA), Ag. Spyridonos Street, 12243 Athens, Greece.ORCID 0000-0003-3915-1829

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microvesicles (MVs) are extracellular vesicles released from many cell types under physiological and pathological conditions, influencing viral transmission, immune regulation, and inflammation. This exploratory pilot study characterized and compared plasma MV profiles in patients infected with human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Plasma samples (n = 125; HIV: 25, HBV: 50, HCV: 50) were analyzed using nanoparticle tracking analysis (NanoSight NS300) to assess MV size and concentration, classifying them as small (<300 nm) or large (>300 nm). Patients with HBV exhibited significantly larger mean MV size compared with both patients with HIV (131.5 ± 14.6 nm vs. 113.1 ± 14.0 nm,

Indexed as

chronic viral infectionshepatitis B virus (HBV)hepatitis C virus (HCV)human immunodeficiency virus (HIV)microvesicles

Identifiers

PMID41597643
PMCPMC12844017

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.