Evidence mapPaperPMID 41598240Full record

ArticleLife (Basel, Switzerland)2026

Association Among Serum Vitamin D Levels, Visual Field Alterations, and Optical Coherence Tomography Parameters: A Clinical Correlation Study.

Tudor-Corneliu Tarași, Mihaela-Madalina Timofte-Zorila, Filippo Lixi, Mario Troisi, Giuseppe Giannaccare, Luminița Apostu, Ecaterina Anisie, Livio Vitiello, Daniel-Constantin Brănișteanu

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Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tudor-Corneliu TarașiDepartment of Ophthalmology, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Mihaela-Madalina Timofte-ZorilaDepartment of Ophthalmology, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Filippo LixiEye Clinic, Department of Surgical Sciences, University of Cagliari, Via Università 40, 09124 Cagliari, Italy.ORCID 0009-0008-0956-4925
Mario TroisiOphthalmology Unit, Salerno University Hospital, Via San Leonardo, 84131 Salerno, Italy.ORCID 0000-0003-3492-014X
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, Via Università 40, 09124 Cagliari, Italy.ORCID 0000-0003-2617-0289
Luminița ApostuSaint Spiridon Emergency Hospital, 700111 Iasi, Romania.
Ecaterina AnisieSaint Spiridon Emergency Hospital, 700111 Iasi, Romania.
Livio VitielloEye Unit, Luigi Curto Hospital, Azienda Sanitaria Locale Salerno, 84035 Polla, Italy.ORCID 0000-0001-7867-3342
Daniel-Constantin BrănișteanuDepartment of Ophthalmology, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0009-5147-9596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D deficiency is increasingly recognized as a systemic factor influencing retinal health through inflammatory, neuroprotective, and vasculotropic pathways. Evidence regarding early retinal alterations in otherwise healthy adults remains limited. This cross-sectional study evaluated 120 eyes from 60 healthy adults stratified by serum 25(OH)D levels into <30 ng/mL (n = 60) and ≥30 ng/mL (n = 60). All subjects underwent optical coherence tomography (OCT), OCT angiography (OCTA), visual field testing, and contrast sensitivity assessment. Central macular thickness (CMT), ganglion cell complex (GCC) thickness, and perfusion density in the superficial and deep capillary plexuses (SCP, DCP) were compared between groups. Vitamin-D-insufficient eyes showed significantly reduced CMT (267.66 ± 13.31 µm vs. 274.69 ± 14.96 µm;

Indexed as

ganglion cell complex (GCC)neuroretinal integrityoptical coherence tomography angiography (OCTA)retinal microvasculatureretinal perfusionvisual field sensitivityvitamin D deficiency

Identifiers

PMID41598240
PMCPMC12842633

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.