Evidence map›Paper›PMID 41598370›Full record

ArticleJournal of clinical medicine2026

Hepatotoxicity Risk of Isoniazid in Patients with Autoimmune Rheumatic Diseases and Prior Liver Injury Due to Disease-Modifying Antirheumatic Drugs: A Single-Center Experience and Literature Review.

Joy Selene Osorio-Chávez, Virginia Portilla González, Iván Ferraz-Amaro, Santos Castañeda, José Manuel Cifrián Martínez, Ricardo Blanco Alonso

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joy Selene Osorio-ChávezPneumology, Hospital Universitario Marqués de Valdecilla, Valdecilla Santander Research Institute, Immunopathology Group (IDIVAL), 39008 Santander, Spain.
Virginia Portilla GonzálezRheumatology, Hospital Universitario Marqués de Valdecilla, Valdecilla Santander Research Institute, Immunopathology Group (IDIVAL), Avda. Valdecilla s/n, 39008 Santander, Spain.
Iván Ferraz-AmaroRheumatology, Hospital Universitario de Canarias, 38320 Santa Cruz de Tenerife, Spain.ORCID 0000-0003-0197-5267
Santos CastañedaRheumatology, Hospital Universitario La Princesa, IIS-Princesa, 28006 Madrid, Spain.ORCID 0000-0002-7748-853X
José Manuel Cifrián MartínezPneumology, Hospital Universitario Marqués de Valdecilla, Valdecilla Santander Research Institute, Immunopathology Group (IDIVAL), 39008 Santander, Spain.ORCID 0000-0003-3682-0142
Ricardo Blanco AlonsoRheumatology, Hospital Universitario Marqués de Valdecilla, Valdecilla Santander Research Institute, Immunopathology Group (IDIVAL), Avda. Valdecilla s/n, 39008 Santander, Spain.ORCID 0000-0003-2344-2285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DMARDshepatotoxicityimmune-mediated inflammatory diseases (IMIDs)isoniazidlatent tuberculosis infectionmethotrexatepolymedication associations

Identifiers

PMID41598370
PMCPMC12842372

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.