ReviewJournal of clinical medicine2026
Fibroblasts as Immunological Sentinels in Cutaneous Inflammation: A Review.
Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Exploration of Regulatory Elements, MicroRNAs, and Copy Number Variation in Urogenital Chlamydia Reinfection in African American Women.International journal of molecular sciences · 2026Article
- Beyond receptor activation: biased toll-like receptor signaling in periodontal inflammation and regeneration.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibroblasts, traditionally viewed primarily as structural cells responsible for extracellular matrix production and tissue architecture, have emerged as important immunomodulatory players in inflammation. These cells actively participate in inflammatory processes through multiple mechanisms: recognizing and responding to inflammatory stimuli, producing diverse inflammatory mediators, and engaging in complex interactions with various immune cells. This review explores the multifaceted immunomodulatory functions of fibroblasts, including their capacity to sense inflammatory signals, secrete inflammatory mediators, modulate immune cell behavior, and establish a pro-inflammatory microenvironment. Understanding the dynamic role of fibroblasts in inflammatory processes provides insights into inflammatory pathology and may inform the development of novel therapeutic strategies targeting fibroblast-mediated immune modulation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.