Evidence map›Paper›PMID 41599158›Full record

ArticlePharmaceutics2025

Boosting LNP Performance: Higher Concentrations of Lipid Mixtures Improve In Vivo Gene Expression and Storage Stability.

Blerina Shkodra, Ashish Muglikar, Janani Thangapandian, Matthias Schumacher, Burcu Binici, Yvonne Perrie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Blerina ShkodraLeon-nanodrugs GmbH, Am Klopferspitz 19, 82152 Planegg, Germany.ORCID 0000-0003-1176-325X
Ashish MuglikarStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.
Janani ThangapandianLeon-nanodrugs GmbH, Am Klopferspitz 19, 82152 Planegg, Germany.
Matthias SchumacherLeon-nanodrugs GmbH, Am Klopferspitz 19, 82152 Planegg, Germany.ORCID 0000-0001-7207-7355
Burcu BiniciStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.ORCID 0009-0005-7528-7709
Yvonne PerrieStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.ORCID 0000-0001-8497-2541

Funding

leon-nanodrugs GmbH Company financial suppport
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

confined jet-impingementFR-JET®LNP morphologyLNP stabilitymRNA-LNPsmRNA therapeuticsmRNA vaccinesprocess intensificationprocess optimization

Identifiers

PMID41599158
PMCPMC12845254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.