Development of a Microwell System for Reproducible Formation of Homogeneous Cell Spheroids.

Miguel A Reina Mahecha, Ginevra Mariani, Pauline E M van Schaik, Paulien Schaafsma, Theo G van Kooten, Prashant K Sharma, Inge S Zuhorn

Abstract read

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In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miguel A Reina MahechaDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0002-5173-9441

Ginevra MarianiDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.

Pauline E M van SchaikMolecular Neurobiology, Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0003-0343-4528

Paulien SchaafsmaDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0002-3409-7328

Theo G van KootenDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.

Prashant K SharmaDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.

Inge S ZuhornDepartment of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands.ORCID 0000-0002-7695-915X

Funding

Graduate School of medical sciences, University Medical Center Groningen Kolff Institute Grant

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D cell culturecell spheroidsembryoid bodiesmicrowellspluripotent stem cellstumor spheroidsvat photopolymerization

Identifiers

PMID41599163

DOI10.3390/pharmaceutics18010056

PMCPMC12844868

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.