Evidence map›Paper›PMID 41599170›Full record

ReviewPharmaceutics2026

Advances in Nanotechnology-Based Topical Delivery Systems for Skincare Applications.

Ziwei Yan, Sunxin Zhang, Guyuan Wu, Yunxiang Kang, Cong Fu, Zihan Wang, Guoqi Wang, Lu Tang, Wei Wang

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Multi-Kingdom Synergy ofLife (Basel, Switzerland) · 2026
    Review
  2. Selective Modulation ofClinical, cosmetic and investigational dermatology · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ziwei YanNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Sunxin ZhangNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Guyuan WuNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Yunxiang KangNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Cong FuNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Zihan WangNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Guoqi WangNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.
Lu TangInstitute for Experimental Molecular Imaging, Uniklinik RWTH Aachen and Helmholtz Institute for Biomedical Engineering, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-8598-7734
Wei WangNational Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Cosmetics, China Pharmaceutical University, Nanjing 211198, China.ORCID 0000-0002-5386-9530

Funding

National Natural Science Foundation of China 31872756National Natural Science Foundation of China 32071387National Natural Science Foundation of China 82573579
6 · The paper itself

Abstract

The growing demand for effective skincare products that can effectively target specific dermatological concerns has accelerated the development of advanced delivery technologies. Among them, nanocarrier-based topical delivery systems have gained significant attention for their ability to enhance the performance of skincare formulations. Acting as versatile delivery tools, nanocarriers not only stabilize and protect sensitive cosmetic ingredients but also improve their penetration through the skin barrier and enable controlled, sustained, or targeted release. Therefore, this review focuses on the recent achievements of nanocarrier-based topical delivery technology for skincare applications, which systematically summarizes the design principles, mechanisms and functional characteristics of diverse nano-based delivery platforms, including vesicular nanocarriers, lipid-based nanocarriers, emulsion-based nanocarriers, polymeric nanocarriers, inorganic nanoparticles, and inclusion complexes. Meanwhile, these nanocarriers are discussed according to their relevance to the pathogenesis of prevalent skin disorders, highlighting how tailored nanocarriers can address specific therapeutic or cosmetic needs. Overall, this review emphasizes the emerging trends and future perspectives of nanotechnology-based topical delivery systems in modern cosmetology, offering more opportunities for precise, effective and science-driven cosmetic solutions.

Indexed as

nanotechnologyskincareskin penetrationtopical delivery technology

Identifiers

PMID41599170
PMCPMC12844762

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.