Evidence map›Paper›PMID 41599366›Full record

ArticleMolecules (Basel, Switzerland)2026

Characterization and Identification of the Ent-Kaurane Diterpenoids in Isodonis Excisoidis Herba Using UHPLC-LTQ-Orbitrap-MS.

Xiaoya Sun, Lingxia Zhang, Conglong Lian, Suiqing Chen, Liping Dai, Yaozu Han

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoya SunCollaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.
Lingxia ZhangCollaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.
Conglong LianSchool of Pharmacy, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.ORCID 0000-0002-8454-5264
Suiqing ChenCollaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.ORCID 0000-0003-0449-168X
Liping DaiCollaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.
Yaozu HanSchool of Pharmacy, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou 450046, China.

Funding

Joint Fund Project of Science and Technology Research and Development of Henan Province Grant Number: 232301420078Major Increase or Decrease Branch Program of Central level 2060302-1904-24National Key R&D Program of China 2023YFC3504000
6 · The paper itself

Abstract

Isodonis Excisoidis Herba (IEH) is a newly discovered herbal medicine used to treat esophageal cancer, chronic pharyngitis, and hepatitis, and ent-kaurane diterpenoids are its main active components. However, systematic studies on the chemical profile of ent-kaurane diterpenoids are lacking. In this study, UHPLC-LTQ-Orbitrap-MS was performed to investigate the fragmentation behaviors of three different types of ent-kaurane diterpenoids from IEH. Bridgehead-unsubstituted 7,20-epoxy-ent-kaurane diterpenoids yielded ions with typical losses of R

Indexed as

Diterpenes, KauraneDrugs, Chinese HerbalIsodonChromatography, High Pressure LiquidLiquid Chromatography-Mass SpectrometryMass SpectrometryMolecular StructurePlant ExtractsDiterpenes, KauraneDrugs, Chinese HerbalPlant Extractschemical constituentsdiagnostic fragmentationidentificationIsodonis Excisoidis HerbaUHPLC-LTQ-Orbitrap-MS

Identifiers

PMID41599366
PMCPMC12844365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.