Evidence map›Paper›PMID 41599369›Full record

ArticleMolecules (Basel, Switzerland)2026

Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation.

Natalia Ksepka, Natalia Kuzia, Sara Frazzini, Luciana Rossi, Małgorzata Łysek-Gładysińska, Michał Ławiński, Artur Jóźwik

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalia KsepkaDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postępu 36a, Jastrzębiec, 05-552 Magdalenka, Poland.ORCID 0009-0003-2324-7911
Natalia KuziaDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postępu 36a, Jastrzębiec, 05-552 Magdalenka, Poland.ORCID 0009-0007-9103-6111
Sara FrazziniDepartment of Veterinary Medicine and Animal Sciences-DIVAS, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-8810-0003
Luciana RossiDepartment of Veterinary Medicine and Animal Sciences-DIVAS, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0003-1178-4683
Małgorzata Łysek-GładysińskaDivision of Medical Biology, Institute of Biology, University of Jan Kochanowski, 25-406 Kielce, Poland.ORCID 0000-0002-0327-3202
Michał ŁawińskiDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postępu 36a, Jastrzębiec, 05-552 Magdalenka, Poland.ORCID 0000-0001-6129-7723
Artur JóźwikDepartment of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postępu 36a, Jastrzębiec, 05-552 Magdalenka, Poland.ORCID 0000-0001-5546-9891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a major metabolic disorder characterized by hepatic lipid accumulation, oxidative stress, and disturbance of lysosomal degradation. Central to these processes is glutathione (GSH), a key antioxidant regulating redox balance and cellular homeostasis. This study aimed to evaluate the therapeutic potential of two dietary antioxidants-astaxanthin and

Indexed as

AntioxidantsLysosomesNon-alcoholic Fatty Liver DiseaseAnimalsDisease Models, AnimalGlutathioneLiverMaleMiceOxidation-ReductionOxidative StressXanthophyllsAntioxidantsastaxanthineGlutathioneXanthophyllsastaxanthingene expressionkokumlysosomesNAFLDoxidative stress

Identifiers

PMID41599369
PMCPMC12843784

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.