Evidence map›Paper›PMID 41599641›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Ligustilide: A Phytochemical with Potential in Combating Cancer Development and Progression-A Comprehensive and Critical Review.

Victória Dogani Rodrigues, Mayara Longui Cabrini, Eliana de Souza Bastos Mazuqueli Pereira, Manuela Dos Santos Bueno, Virgínia Maria Cavallari Strozze Catharin, Jesselina Francisco Dos Santos Haber, Rachel Gomes Eleutério, Lidiane Indiani, Vitor Cavallari Strozze Catharin, Raquel Cristina Ferraroni Sanches and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Victória Dogani RodriguesDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília 17519-030, São Paulo, Brazil.
Mayara Longui CabriniDepartment of Physiotherapy, School of Physiotherapy, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Eliana de Souza Bastos Mazuqueli PereiraGraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Manuela Dos Santos BuenoGraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Virgínia Maria Cavallari Strozze CatharinGraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Jesselina Francisco Dos Santos HaberDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Rachel Gomes EleutérioDepartment of Odontology, School of Dentistry, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Lidiane IndianiDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Vitor Cavallari Strozze CatharinDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Raquel Cristina Ferraroni SanchesGraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Flávia Cristina Castilho CarácioDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília 17519-030, São Paulo, Brazil.
Tereza Lais Menegucci ZutinGraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Vitor Engrácia ValentiFaculty of Philosophy and Sciences, Universidade Estadual Paulista (UNESP), Marília 17525-900, São Paulo, Brazil.ORCID 0000-0001-7477-3805
Sandra Maria BarbalhoDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.ORCID 0000-0002-5035-876X
Lucas Fornari LaurindoDivision of Cellular Growth, Hemodynamic, and Homeostasis Disorders, Graduate Program in Medical Sciences, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo 01246-903, São Paulo, Brazil.ORCID 0000-0003-3159-0982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains one of the leading global health challenges, with increasing resistance to conventional therapies hindering treatment efficacy. Ligustilide, a bioactive compound derived from

Indexed as

cancercancer developmentcancer progressionLigustilidemalignanciesmetastasis(Z)-Ligustilide

Identifiers

PMID41599641
PMCPMC12845225

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.