Evidence mapPaperPMID 41599649Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Integrative Multi-Omics Elucidates the Therapeutic Effect of Coix Seed Oil on Rheumatoid Arthritis via the Gut-Butyrate-Joint Axis and NLRP3 Inflammasome Suppression.

Fanxin Ouyang, Xiaoyu Zhang, Rui Miao, Hongxi Kong, Wenxin Zhang, Zhidan Wang, Xu Han, Shuang Ren, Jie Zhang, Fanyan Meng

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fanxin OuyangNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.ORCID 0000-0002-5972-8552
Xiaoyu ZhangSchool of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.ORCID 0009-0005-6978-8064
Rui MiaoSchool of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.ORCID 0009-0001-4707-5937
Hongxi KongNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.
Wenxin ZhangSchool of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China.
Zhidan WangNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.
Xu HanNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.
Shuang RenNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.
Jie ZhangNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.ORCID 0000-0003-2972-3870
Fanyan MengNational Regional Diagnosis and Treatment Center for TCM Rheumatology, The First Hospital of China Medical University, China Medical University, Shenyang 110001, China.

Funding

National Natural Science Foundation of China NO.81973661National Natural Science Foundation of China NO.82104828Xingliao Talent Program Medical Experts Project YXMJ-MZY-12Xingliao Talent Program Medical Experts Project YXMJ-QNMZY-10
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

butyric acidCoix seed oilgut microbiotaNLRP3 inflammasomerheumatoid arthritis

Identifiers

PMID41599649
PMCPMC12844696

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.