Targeting Infected Host Cell Heme Metabolism to Kill Malaria Parasites.

Faiza A Siddiqui, Swamy R Adapa, Xiaolian Li, Jun Miao, Liwang Cui, Rays H Y Jiang

Abstract read

In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

The Queen and the Dark Twin: Heme, Protoporphyrin IX, and State Transitions in Liver Metabolism.Molecules (Basel, Switzerland) · 2026
Review
Russian Dolls of Heme Metabolism in Malaria-Infected Red Blood Cells: Nested Vulnerabilities and Therapeutic Opportunities.Pathogens (Basel, Switzerland) · 2026
Review
5-ALA does not potentiate dihydroartemisinin against Plasmodium falciparum malaria parasites.EMBO molecular medicine · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faiza A SiddiquiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.

Swamy R AdapaGlobal Health, College of Public Health, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0003-3313-2782

Xiaolian LiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.

Jun MiaoDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0001-9374-6749

Liwang CuiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0002-8338-1974

Rays H Y JiangGlobal Health, College of Public Health, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0001-8982-4169

Funding

Unraveling the Drivers of Persistent Malaria Transmission in Cameroon: A Systems Approach (REDIAL)U19AI181593 · UNIVERSITY OF SOUTH FLORIDA · 2025 to 2025

$745k

NIAID NIH HHS U19 AI181593USF COPH Research Award

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

artemisininerythrocytehememalariaporphyrinprotoporphyrin IX

Identifiers

PMID41599764

DOI10.3390/ph19010167

PMCPMC12845165

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.