Evidence map›Paper›PMID 41599939›Full record

Observational studyNutrients2026

Vitamin D Status in Rheumatology Patients with Inflammatory Compared with Non-Inflammatory Diagnoses: Inflammatory and Autoimmune Markers Are Not Associated with Vitamin D Levels.

Arne Schäfer, Magdolna Szilvia Kovacs, Axel Nigg, Martin Feuchtenberger

Abstract readObservational Study
In one paragraph

Observational study in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arne SchäferMedizinische Klinik und Poliklinik II, University Hospital Würzburg, 97080 Wuerzburg, Germany.ORCID 0000-0001-6600-3691
Magdolna Szilvia KovacsRheumatologie, Medizinisches Versorgungszentrum (MVZ) MED BAYERN OST, 84489 Burghausen, Germany.ORCID 0000-0001-9215-6501
Axel NiggRheumatologie, Medizinisches Versorgungszentrum (MVZ) MED BAYERN OST, 84489 Burghausen, Germany.ORCID 0000-0001-5805-806X
Martin FeuchtenbergerMedizinische Klinik und Poliklinik II, University Hospital Würzburg, 97080 Wuerzburg, Germany.ORCID 0000-0001-8028-8099

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesVitamin D levels tend to be lower in patients with inflammatory rheumatic diseases (IRDs), including rheumatoid arthritis (RA), but there are minimal data on vitamin D levels in rheumatology patients with inflammatory vs. non-inflammatory diagnoses.

methodsIn this retrospective, observational study, we used electronic health record data from patients presenting for their first visit at a large rheumatology clinic to assess vitamin D levels and deficiency based on diagnosis, and to evaluate the association between vitamin D and inflammatory markers (including C-reactive protein [CRP]) or autoimmune markers (including rheumatoid factor [RF], anti-citrullinated peptide antibody, and anti-nuclear antibodies). Logistic regression analysis with 13 clinical variables was used to evaluate the association between vitamin D levels and IRD diagnosis, and linear regression was used to evaluate the association between vitamin D levels and CRP or RF.

resultsThe patient cohort included 4979 patients; 1385 (27.8%) had an IRD. Vitamin D levels were significantly lower in the IRD vs. non-inflammatory subgroup (mean [SD] of 26.6 [13.3] vs. 27.7 [14.3];

conclusionsWe conclude that vitamin D levels do not differ substantially based on IRD versus non-inflammatory diagnosis, CRP levels, or RF levels in this clinical cohort.

Indexed as

InflammationRheumatic DiseasesVitamin DVitamin D DeficiencyAdultAgedAnti-Citrullinated Protein AntibodiesArthritis, RheumatoidBiomarkersC-Reactive ProteinFemaleHumansMaleMiddle AgedRetrospective StudiesRheumatoid FactorAnti-Citrullinated Protein AntibodiesBiomarkersC-Reactive ProteinRheumatoid FactorVitamin DC-reactive proteinelectronic health recordsepidemiologyinflammatory rheumatic diseaserheumatoid factorrheumatologyvitamin D

Identifiers

PMID41599939
PMCPMC12844765

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.