Evidence map›Paper›PMID 41599954›Full record

ArticleNutrients2026

Lithocholic Acid Restores Gut Microbiota and Bile Acid Homeostasis to Improve Type 2 Diabetes.

Han Ge, Mengxiao Guo, Xin Chen, Lu Chen, Xin Yang, Dingzuo Ge, Liqiang Guo, Yue Luo, Guangbo Ge, Lei Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Han GeShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Mengxiao GuoShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xin ChenShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Lu ChenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xin YangSection of Endocrinology, Internal Medicine, School of Medicine, Yale University, New Haven, CT 06510, USA.ORCID 0000-0001-7799-7425
Dingzuo GeShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Liqiang GuoShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yue LuoShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Guangbo GeState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Lei ZhangShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ruirui WangShanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Funding

Open Project of the State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine LSLSKL20240131Science and Technology Development Program of Shanghai University of Traditional Chinese Medicine 24KFL019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bile Acids and SaltsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Gastrointestinal MicrobiomeHomeostasisLithocholic AcidAnimalsBlood GlucoseDiet, High-FatFatty Acids, VolatileFecesInsulinInsulin ResistanceIntestinal Barrier FunctionMaleMiceBile Acids and SaltsBlood GlucoseFatty Acids, VolatileGpbar1 protein, mouseInsulinLithocholic AcidReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearReceptors, G-Protein-CoupledA. muciniphilabile acidsgut microbiotalithocholic acid (LCA)type 2 diabetes mellitus

Identifiers

PMID41599954
PMCPMC12845021

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.