Evidence map›Paper›PMID 41600947›Full record

ArticleVaccines2025

Development and Immunogenicity Assessment of a Multi-Epitope Antigen Against Zika Virus: An In Silico and In Vivo Approach.

Lígia Rosa Sales Leal, Matheus Gardini Amâncio Marques de Sena, Maria da Conceição Viana Invenção, Ingrid Andrêssa de Moura, André Luiz Santos de Jesus, Georon Ferreira de Sousa, Bárbara Rafaela da Silva Barros, Cristiane Moutinho Lagos de Melo, Lindomar José Pena, Francesca Paolini and 3 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lígia Rosa Sales LealLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-4453-8238
Matheus Gardini Amâncio Marques de SenaLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0009-0008-1573-3000
Maria da Conceição Viana InvençãoLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0001-9360-1275
Ingrid Andrêssa de MouraLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-0715-8674
André Luiz Santos de JesusFederal Institute of Education, Science and Technology of Mato Grosso-Lucas do Rio Verde Advanced Campus, Lucas do Rio Verde 78455-000, Brazil.ORCID 0000-0003-2335-5712
Georon Ferreira de SousaLaboratory of Immunological and Antitumor Analysis, Keizo Asami Immunopathology Laboratory, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0001-8780-202X
Bárbara Rafaela da Silva BarrosLaboratory of Immunological and Antitumor Analysis, Keizo Asami Immunopathology Laboratory, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Recife 50670-901, Brazil.
Cristiane Moutinho Lagos de MeloLaboratory of Immunological and Antitumor Analysis, Keizo Asami Immunopathology Laboratory, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-8831-0163
Lindomar José PenaDepartment of Virology and Experimental Therapy, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife 50740-465, Brazil.ORCID 0000-0003-1134-5699
Francesca PaoliniHPV-UNIT-UOSD Tumor Immunology and Immunotherapy, IRCCS Regina Elena National Cancer Institute, 00128 Rome, Italy.ORCID 0000-0002-7384-6248
Aldo VenutiLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0003-2322-6857
Anna Jéssica Duarte SilvaLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-8341-7877
Antonio Carlos de FreitasLaboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-4957-9549

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88882.379743/2019-01Fundação de Amparo à Ciência e Tecnologia de Pernambuco APQ-01482-2.02/22National Council for Scientific and Technological Development 308684/2023-0
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA vaccineimmunoinformaticsmultiepitopesssPGIPZika virus

Identifiers

PMID41600947
PMCPMC12846674

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.