ArticleThe Journal of physiology2026
Distinct developmental dynamics of opposing persistent currents shape motoneuron firing during motor maturation of zebrafish.
Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Zebrafish rapidly acquire new locomotor movements during the first few days of development. Rapid, ballistic movements relying on early-born primary motoneurons are supplemented with slower, more co-ordinated movements relying on later-born secondary motoneurons. We demonstrate distinct developmental dynamics of two persistent ionic currents related to locomotor rhythmogenesis in primary motoneurons during early development. From 2 to 5 days post-fertilization (dpf), a riluzole-sensitive persistent inward Na
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