SynthesisFrontiers in psychiatry2025
Effectiveness of unguided digital cognitive behavioral therapy for insomnia on depressive symptoms: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to assess the intervention effects of unguided digital cognitive behavioral therapy for insomnia (dCBT-I) on patients with comorbid depression and insomnia through a systematic review and meta-analysis, in order to determine its effectiveness as a treatment strategy for comorbid depression and insomnia. Methods: We conducted a systematic search across PubMed, Cochrane, Embase, ClinicalTrials.gov, and PsycINFO.databases to identify randomized controlled trials (RCTs) focusing on adults with comorbid insomnia and depressive symptoms, excluding those with severe physical illnesses or psychiatric disorders. Following the removal of duplicates, 1842 articles were screened, resulting in the inclusion of 16 RCTs in the final meta-analysis. Results: Post-treatment evaluations revealed that digital cognitive behavioral therapy for insomnia (dCBT-I) demonstrated a significant impact on insomnia (SMD = -0.94; 95% CI: -1.40 to -0.48; Conclusions: This meta-analysis evaluated the efficacy of therapist-unguided digital cognitive behavioral therapy (dCBT-I) for insomnia and depression, dCBT-I demonstrated significant reductions in insomnia severity and depressive symptoms within the studied population, despite substantial heterogeneity. It also demonstrated moderate to large effects for moderate-to-severe depression, further supporting the effectiveness of unguided dCBT-I. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251044042, identifier CRD420251044042.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.