Evidence map›Paper›PMID 41601552›Full record

ReviewIBRO neuroscience reports2025

Mechanisms and research progress of insect-derived medicines in intervention for ischemic stroke.

Chenxi Xu, Yunxiang Guan

Abstract readReview
In one paragraph

Review in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chenxi XuDepartment of Encephalopathy, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Yunxiang GuanDepartment of Encephalopathy, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a severe neurological disorder caused by the rupture or blockage of blood vessels, leading to significant mortality and disability. Approximately 87 % of cases can be attributed to ischemic stroke. In China, ischemic stroke is the leading cause of death among adults. Current treatments for cerebral infarction mainly include thrombolysis, antiplatelet therapy, anticoagulation, and vasodilation. However, their efficacy in preventing or mitigating primary brain injury remains inadequate. In recent years, traditional Chinese medicine (TCM) has garnered increasing attention due to its proven efficacy and low toxicity. Numerous studies report that TCM formulas, extracts, and compound preparations exhibit pro-angiogenic activity. Insect-derived medicines, known for their actions in detoxification, eliminating pathogens, breaking blood stasis, resolving blood stasis, dispelling wind, and unblocking collaterals, show favorable efficacy in treating ischemic stroke. This paper summarizes several insect-derived medicines and their active components, elucidates their mechanisms of action in antithrombosis, neuroprotection, anti-inflammation, and antioxidation, and discusses current clinical applications and future research directions.

Indexed as

Cerebral infarctionClinical applicationInsect-derived medicinesTraditional Chinese medicine

Identifiers

PMID41601552
PMCPMC12834020

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.