ArticleFrontiers in medicine2025
Prognostic value of combined stratification using TyG index and CD4
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Triglyceride-glucose index and short-term mortality of adult patients with sepsis: a meta-analysis.Frontiers in endocrinology · 2026Pooled it
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Sepsis contributes to global mortality due to chronic immunodeficiency and metabolic disturbances, particularly in those infected with the human immunodeficiency virus (HIV). The TyG index and CD4 Methods: Clinical data were retrospectively collected from patients admitted to the Eighth Affiliated Hospital of Guangzhou Medical University. The participants were stratified into four risk categories according to their TyG index and CD4 Results: Among 1,278 patients with HIV-associated sepsis, 847 had CD4 counts <50 cells/μL. The Kaplan-Meier analysis revealed progressively higher 7-day and 28-day all-cause mortality rates across these strata, with the highest mortality in the low CD4 Conclusion: A combined TyG-CD4 assessment provides a rapid and straightforward means of integrating metabolic and immunological insights to identify high-risk individuals early, thereby generating hypotheses for future trials of personalized therapeutic strategies.
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