Evidence map›Paper›PMID 41601791›Full record

ArticleFrontiers in medicine2025

Carlo Valsecchi, Eleonora Carlesso, Michele Battistin, Sebastiano M Colombo, Emanuele Cattaneo, Francesca Gori, Thomas Langer, Giacomo Grasselli, Alberto Zanella

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlo Valsecchi *Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Eleonora Carlesso *Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Michele BattistinCenter for Preclinical Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Sebastiano M ColomboDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Emanuele CattaneoDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Francesca GoriDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Thomas LangerDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Giacomo GrasselliDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.
Alberto ZanellaDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Efficient oxygen transport depends on hemoglobin (Hb) affinity for O Methods: Blood from six healthy volunteers was equilibrated at 37°C with gas mixtures spanning PO Results: HbO Conclusion: These findings, validated against external datasets, underscore the tight coupling between respiratory gas exchange and electrolyte homeostasis. The study provides novel insights into how CO

Indexed as

bloodcarbon dioxideelectrolyteserythrocytehemoglobinoxygenphysiology

Identifiers

PMID41601791
PMCPMC12833093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.