Evidence map›Paper›PMID 41601868›Full record

ArticleFrontiers in nutrition2025

Preliminary evaluation of an extract of

Alessia Mattiello, Gloria Barbaglio, Mirko Magnone, Sonia Scarfì, Stefania Vernazza, Serena Mirata, Jan Markus, Silvia Letasiova, Danilo Riva, Roberto Premoli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessia MattielloNatIng Italia Srl, Casalpusterlengo, Lodi, Italy.
Gloria BarbaglioNatIng Italia Srl, Casalpusterlengo, Lodi, Italy.
Mirko MagnoneDIMES, University of Genova, Genova, Italy.
Sonia ScarfìDISTAV, University of Genova, Genova, Italy.
Stefania VernazzaDIMES, University of Genova, Genova, Italy.
Serena MirataDISTAV, University of Genova, Genova, Italy.
Jan MarkusMatTek In Vitro Life Science Laboratories, Bratislava, Slovakia.
Silvia LetasiovaMatTek In Vitro Life Science Laboratories, Bratislava, Slovakia.
Danilo RivaNova Argentia, Gorgonzola, Milan, Italy.
Roberto PremoliNatIng Italia Srl, Casalpusterlengo, Lodi, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The increasing prevalence of metabolic syndrome has prompted the development of nutraceuticals to support the management of glucose intolerance and dyslipidemia. Methods: A novel ingredient derived from Results: The extract significantly inhibited key enzymes involved in carbohydrate metabolism and reduced glucose and cholesterol absorption in a three-dimensional intestinal model, while showing antioxidant activity. Preliminary human observations indicated improvements in HbA1c, post-prandial glucose, BMI, and a trend toward reduced total and LDL cholesterol. Discussion: These results suggest that

Indexed as

Amaranthus caudatusantioxidant activitycholesterol absorptionglucose absorptionglycemic controlmetabolic syndromenutraceutical

Identifiers

PMID41601868
PMCPMC12833965

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.