ArticleFrontiers in endocrinology2025
Remnant cholesterol: an independent, dose-dependent risk factor for hyperuricemia in a normolipidemic chinese population.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association between numbing-spicy related dietary behavior and hyperuricemia in a Southwestern Chinese population.Frontiers in nutrition · 2026Article
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2 authors.
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Abstract
Backgroud: The association between remnant cholesterol (RC) and hyperuricemia (HUA) remains unclear in the general population with entirely normal lipid profiles and no prior lipid-lowering therapy. This study aimed to investigate the association between RC and HUA in a normolipidemic Chinese population. Method: We recruited 2,171 participants aged 30-79 years from Rongchang, Chongqing Municipality, southwest China, as part of the China Multi-Ethnic Cohort Study. Logistic regression, restricted cubic spline (RCS), and mediation analyses were applied to evaluate the association between RC and HUA. Furthermore, subgroup and sensitivity analyses were conducted to assess the consistency of the findings. Results: A total of 2,171 participants were enrolled, with a mean (SD) age of 50.43 (12.21) years. The overall prevalence of HUA was 9.07%, and the prevalence across RC quartiles (Q1: 0.14-0.43, Q2: 0.44-0.60, Q3: 0.61-0.89, and Q4: ≥0.90 mmol/L) were increased stepwise: 4.45%, 8.32%, 12.88%, and 19.08%, respectively( Conclusion: Remnant cholesterol emerges as a fully independent, dose-dependent, and readily modifiable determinant of incident hyperuricemia in Chinese adults, which can serve as an ideal candidate for inclusion in routine metabolic panels and presenting as a hypothesis for future longitudinal research.
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