Evidence map›Paper›PMID 41602114›Full record

ArticleFrontiers in cellular and infection microbiology2025

The lichen secondary metabolite lichesterinic acid exhibits antibiofilm activity against fungal pathogens.

Martin N Odabas, Katharina Kainz, Ingo Weinberger, Kerstin Schloffer, Sabrina Riedl, Marylène Chollet-Krugler, Dagmar Zweytick, Joël Boustie, Frank Madeo, Didac Carmona-Gutierrez

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Martin N OdabasInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Katharina KainzInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Ingo WeinbergerInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Kerstin SchlofferInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Sabrina RiedlInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Marylène Chollet-KruglerCNRS, Institut des Sciences Chimiques de Rennes-UMR 6226, Univ Rennes, Rennes, France.
Dagmar ZweytickInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Joël BoustieCNRS, Institut des Sciences Chimiques de Rennes-UMR 6226, Univ Rennes, Rennes, France.
Frank MadeoInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Didac Carmona-GutierrezInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lichens are well known for producing unique secondary metabolites, some of which have been shown to exhibit medically relevant bioactivities, including antimicrobial effects. With the increasing prevalence of fungal infections and the growing resistance to commonly used antimycotics, there is an urgent need for new antifungal agents, especially for aged and/or immunocompromised individuals. In this study, we screened a collection of lichen-derived metabolites for antifungal properties in two medically relevant fungal pathogens,

Indexed as

Antifungal AgentsBiofilmsCandida albicansLichensAnimalsHumansMicrobial Sensitivity TestsSecondary MetabolismAntifungal Agentsantimycoticsbiofilm eradicationbiofilm inhibitionCandida albicansCandida glabratadrugresistanceyeast

Identifiers

PMID41602114
PMCPMC12832668

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.