Evidence mapPaperPMID 41602471Full record

ReviewFrontiers in bioengineering and biotechnology2025

Natural polymers in diabetes management: formulation prospects of

Nsibambi Ronald Kizza, Sarad Pawar Naik Bukke, Ungo-Kore Hussain Yahaya, Yakubu Sunday Bot

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nsibambi Ronald KizzaDepartment of Pharmaceutics and Pharmaceutical Technology, Kampala International University, Ishaka, Bushenyi, Uganda.
Sarad Pawar Naik BukkeDepartment of Pharmaceutics and Pharmaceutical Technology, Kampala International University, Ishaka, Bushenyi, Uganda.
Ungo-Kore Hussain YahayaDepartment of Pharmaceutics and Pharmaceutical Technology, Kampala International University, Ishaka, Bushenyi, Uganda.
Yakubu Sunday BotDepartment of Medical Laboratory Science, Kampala International University, Ishaka, Bushenyi, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is a long-term metabolic disorder distinguished by hyperglycemia with the limitation of severe complications unless treated effectively. Metformin is the first-line agent for treating diabetes type 2 but has the drawback of a short half-life, incomplete absorption and is associated with gastrointestinal side effects requiring multiple times a day dosing. Sustained release (SR) formulations have been explored for the delivery of metformin while prolonging plasma levels, decreasing the frequency of dosing and increasing adherence improve patient compliance and outcomes related to diabetes. Some natural polymers have attracted attention as excipients for SR systems because they are biocompatible, biodegradable, and cost-effective. Specifically,

Indexed as

diabetes managementHibiscus rosa-sinensis mucilagematrix tabletsmetforminnatural polymerssustained release

Identifiers

PMID41602471
PMCPMC12832763

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.