Evidence map›Paper›PMID 41602970›Full record

SynthesisFrontiers in neurology2025

Effects of robotic-assisted upper extremity therapy for stroke patients in different recovery phases: a systematic review and meta-analysis.

Lulu Wang, Xiaoling Li, Yan Liu, Enyu Zhang, Cuiting Li

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lulu WangDepartment of Rehabilitation Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Xiaoling LiDepartment of Rehabilitation Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Yan LiuDepartment of Rehabilitation Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Enyu ZhangDepartment of Rehabilitation Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Cuiting LiDepartment of Rehabilitation Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the efficacy of robotic-assisted therapy on upper extremity recovery after stroke through stratified meta-analysis, assessing the influence of disease phase, injury severity, device type, training parameters, and follow-up duration. Methods: We conducted a systematic literature search of PubMed, Embase, Cochrane Library, and Web of Science from inception to July 2025 for randomized controlled trials (RCTs) comparing robotic-assisted with conventional upper limb therapy in adult stroke patients. Results: Analysis of 42 RCTs ( Conclusion: Robotic-assisted therapy significantly improves upper extremity motor function and activities of daily living after stroke, with clinically meaningful gains particularly evident in subacute patients and those with severe impairment. Benefits in grip strength and social participation were statistically significant but of uncertain clinical importance due to methodological limitations. These findings support a stratified rehabilitation approach, prioritizing subacute and severely impaired patients for robotic intervention to maximize functional outcomes. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42025640276, CRD42025640276.

Indexed as

meta-analysisneuronal plasticityrandomized controlled trialrehabilitationroboticsstrokeupper extremity

Identifiers

PMID41602970
PMCPMC12832252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.