Evidence map›Paper›PMID 41603336›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Caregiver burden and quality of life associated with behavioral and psychological symptoms of Alzheimer's disease: A web-based cross-sectional survey study.

Shunichiro Shinagawa, Tomoyuki Nagata, Shinichi Noto, Kentaro Yamato, Naoki Mori, Keisuke Onuki

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Toward Precision Neuropsychiatry of Dementia: Neuropsychiatric Symptoms as Multidimensional Clinical Phenotypes.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026
    Review
  2. Potential of ASCOT-Carer for evaluating the quality of life of family caregivers for patients with Alzheimer's disease in Japan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shunichiro ShinagawaDepartment of Psychiatry, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.ORCID 0000-0002-5952-6141
Tomoyuki NagataDepartment of Psychiatry, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.ORCID 0000-0002-8731-9887
Shinichi NotoDepartment of Rehabilitation, Niigata University of Health and Welfare, Niigata-shi, Niigata, Japan.ORCID 0000-0002-6952-7770
Kentaro YamatoMedical Affairs, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan.ORCID 0000-0002-5027-6289
Naoki MoriMedical Affairs, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan.ORCID 0009-0000-9948-5260
Keisuke OnukiMedical Affairs, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan.ORCID 0000-0001-6395-5275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundBehavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease (AD) may seriously impact caregiver burden and, therefore, quality of care.ObjectiveTo clarify the association of BPSD and BPSD subtypes with caregiver burden and quality of life (QOL) among caregivers of patients with AD in Japan in a multidimensional manner.MethodsThis descriptive, cross-sectional, community-based survey involved administering a web-based questionnaire to live-in caregivers of patients with AD registered with Macromill Inc. BPSD prevalence was measured using the Japanese version of the Neuropsychiatric Inventory-Questionnaire Form. The Japanese version of the Zarit Caregiver Burden Scale (J-ZBI), EQ-5D-5L, and Adult Social Care Outcomes Toolkit for Carers (ASCOT-Carer) were used to assess caregiver burden, health-related QOL, and social care-related QOL, respectively.ResultsOf 705 survey responders, 639 (90.6%) and 66 (9.4%) cared for patients with and without BPSD, respectively. Mean caregiver age was 54.6 years, 56.9% were male, and 84.0% cared for parents or in-laws. In the "with BPSD" group, the J-ZBI score was higher (mean difference [95% confidence interval], 6.7 [4.5, 9.0];

Indexed as

Alzheimer DiseaseCaregiver BurdenCaregiversCost of IllnessQuality of LifeAdultAgedCross-Sectional StudiesFemaleHumansInternetJapanMaleMiddle AgedSurveys and QuestionnairesAlzheimer's diseasebehavioral symptomscaregiver burdencaregiversdementiapsychomotor agitationquality of life

Identifiers

PMID41603336
PMCPMC13172382

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.