Evidence map›Paper›PMID 41604247›Full record

ArticleeLife2026

Cryo-EM structure revealed a novel F-actin binding motif in a

Wenjie W Zeng, Garrison Komaniecki, Jiaze Liu, Hening Lin, Yuxin Mao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Life science alliance · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Wenjie W ZengWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0003-1028-7845
Garrison KomanieckiDepartment of Chemistry, Department of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Jiaze LiuDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.ORCID https://orcid.org/0009-0002-9962-8086
Hening LinDepartment of Chemistry, Department of Molecular Biology and Genetics, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0002-0255-2701
Yuxin MaoWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0002-5064-1397

Funding

Design and development of HDAC11-specific chemical inhibitors for disease treatmentsR01AI153110 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI LIN, HENING, MILLER, ROBERT H. · 2021 to 2025
$3.5M
Di-ubiquitin modification of ubiquitin ligase adaptors in membrane protein downregulationR01GM144452 · NIGMS · CORNELL UNIVERSITY · PI EMR, SCOTT D, MAO, YUXIN · 2022 to 2025
$1.6M
Non-canonical phosphoribosyl ubiquitination and de-ubiquitination by legionella effectors (McMillan Supplement 2023)R01GM135379 · NIGMS · CORNELL UNIVERSITY · PI MAO, YUXIN · 2020 to 2023
$1.3M
Ubiquitin mechanism in health and pathogen-host interactionsR35GM156204 · NIGMS · CORNELL UNIVERSITY · PI Yuxin Mao · 2025 to 2026
$778k
Cornell University the Sadov Graduate Student FellowshipNIAID NIH HHS R01 AI153110NIGMS NIH HHS R01 GM135379NIGMS NIH HHS R01 GM144452NIGMS NIH HHS R35 GM156204NIH HHS R01AI153110NIH HHS R01GM144452NIH HHS T32
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ActinsAcyltransferasesBacterial ProteinsLegionella pneumophilaAmino Acid MotifsCryoelectron MicroscopyHumansModels, MolecularProtein BindingActinsAcyltransferasesBacterial Proteinsactin-binding proteinF-actinfatty-acylationlegionella pneumophilaLegionella pneumophilamolecular biophysicssmall GTPasesstructural biology

Identifiers

PMID41604247
PMCPMC12851578

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.