Evidence map›Paper›PMID 41604320›Full record

Observational studyInterdisciplinary cardiovascular and thoracic surgery2026

Minimally Invasive Mitral Valve Surgery Compared to Sternotomy in Patients Over 70 Years Old: A Retrospective Nationwide Multicentre Study in The Netherlands.

Andrew Tjon Joek Tjien, Kinsing Ko, Samuel Heuts, Saskia Houterman, Maaike Roefs, Sjoerd Bouwmeester, Pim Tonino, Sandeep Singh, Robert Storm van Leeuwen, Jos Maessen and 4 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andrew Tjon Joek TjienDepartment of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, 5623 EJ, The Netherlands.
Kinsing KoDepartment of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands.ORCID 0000-0001-5277-9448
Samuel HeutsDepartment of Cardiothoracic Surgery, Maastricht University Medical Center, Maastricht, 6229 HX, The Netherlands.ORCID 0000-0003-3531-9997
Saskia HoutermanNetherlands Heart Registration, Utrecht, 3511 EP, The Netherlands.
Maaike RoefsNetherlands Heart Registration, Utrecht, 3511 EP, The Netherlands.
Sjoerd BouwmeesterDepartment of Cardiology, Catharina Hospital, Eindhoven, 5623 EJ, The Netherlands.ORCID 0000-0002-8358-2231
Pim ToninoDepartment of Cardiology, Catharina Hospital, Eindhoven, 5623 EJ, The Netherlands.
Sandeep SinghDepartment of Cardiothoracic Surgery, Isala, Zwolle, 8025 AB, The Netherlands.
Robert Storm van LeeuwenDepartment of Cardiothoracic Surgery, Isala, Zwolle, 8025 AB, The Netherlands.
Jos MaessenDepartment of Cardiothoracic Surgery, Maastricht University Medical Center, Maastricht, 6229 HX, The Netherlands.
Peyman Sardari NiaDepartment of Cardiothoracic Surgery, Maastricht University Medical Center, Maastricht, 6229 HX, The Netherlands.ORCID 0000-0003-2296-1497
Niels VerberkmoesDepartment of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, 5623 EJ, The Netherlands.
Jules OlsthoornDepartment of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, 5623 EJ, The Netherlands.ORCID 0000-0002-9678-3315
Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOlder patients are more prone to postoperative morbidity and mortality after mitral valve (MV) surgery. Minimally invasive MV surgery (MIMVS) is increasingly adopted worldwide, with a potential benefit in the elderly. This study compares short-term and mid-term outcomes in patients above 70 years, undergoing MIMVS versus median sternotomy (MST), in a nationwide registry.

methodsAll patients above 70 years undergoing primary elective MV surgery (±tricuspid valve [TV] surgery, atrial septal defect closure, rhythm surgery) between 2013 and 2021 were included. All data were extracted from the Netherlands Heart Registration. Primary outcomes were short-term morbidity, mortality, and 5-year survival.

resultsIn total, 1418 patients were included (MST n = 797, MIMVS n = 621). No statistically significant differences in baseline characteristics were found. Median Logistic EuroSCORE I was 6.3 [4.7-8.5] vs 6.0 [4.6-8.5], P = .27 for MST and MIMVS, respectively. Mitral valve repair (77.7% vs 64.7% P < .001) and concomitant TV surgery (43.9% vs 18.2%, P < .001) was more frequently performed in MST. Lower 30-day mortality was observed in MIMVS (0.6% [n = 4] vs 2.5% [n = 21], P = .01). Furthermore, the incidence of pneumonia, prolonged intubation, readmission to intensive care unit, kidney failure, and new-onset arrhythmia were lower for MIMVS. No difference in 5-year survival was found (MST: 89.1 ± 4.6% vs MIMVS: 91.6 ± 4.7% Log-Rank P = .51).

conclusionsMinimally invasive MV surgery in patients above 70 years may be associated with lower 30-day mortality and incidence of postoperative complications compared with sternotomy.

Indexed as

Cardiac Surgical ProceduresHeart Valve DiseasesMinimally Invasive Surgical ProceduresMitral ValveSternotomyAgedAged, 80 and overAge FactorsFemaleHumansMaleNetherlandsPostoperative ComplicationsRegistriesRetrospective StudiesRisk Factorsminimally invasive mitral valve surgerymitral valve surgerynationwide registrypatients over 70 years old

Identifiers

PMID41604320
PMCPMC12881947

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.