ArticleNeuroepidemiology2026
A Global, Regional, and National Survey on Burden and Quality of Care Index of Alzheimer's Disease and Other Dementias in Adults Aged 55 and Above: The Global Burden of Disease Study 1990-2021.
Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAlzheimer's disease and other dementias (ADOD) represent a growing global health challenge. This study aims to propose a comprehensive measure called the quality of care index (QCI) to assess disparities in quality of care (QC) for ADOD patients across global, regional, and national levels. We also evaluate temporal trends in QCI and explore associations with socioeconomic development, gender, and age.
methodsIndividuals aged 55 years and older with ADOD were included in this longitudinal study using data from the global burden of disease (GBD) database spanning 1990-2021. The QCI score was calculated using four indicators. Principal component analysis was employed to compute the QCI. The QCI was rescaled to a single index ranging from 0 to 100, where higher scores indicate better QC.
resultsThe global QCI increased from 32.9 in 1990 to 50.2 in 2021, with a greater increase among females (68.8%) than males (52.4%). Significant gains were observed in regions with middle and high-middle sociodemographic index), while slight declines occurred in high- and low-middle SDI regions, and slow progress was seen in low SDI regions. The gender gap in QCI narrowed, with females outperforming males in low SDI regions. QCI scores showed a marked increase with age, reflecting lower QC access in younger age groups and a sharp rise in older age groups.
conclusionSubstantial disparities in QCI exist globally and regionally across age cohorts and between men and women. Policymakers should prioritize targeted interventions to address these gaps, improve access to high-quality care, and alleviate the global burden of ADOD.
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