Evidence mapPaperPMID 41604485Full record

ReviewScience advances2026

From light to sound: Seeing and hearing the placenta in health and disease.

Donghyun Lee, Jiwoong Kim, Jinseok Heo, Hyunseo Jeon, Shiyang Chang, Wonseok Choi, Chulhong Kim, Zhifen Yang

Abstract readReview
In one paragraph

Review in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donghyun LeeDepartments of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, and Medical Science and Engineering, POSTECH-CATHOLIC Biomedical Engineering Institute, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0009-0008-7620-4348
Jiwoong KimDepartments of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, and Medical Science and Engineering, POSTECH-CATHOLIC Biomedical Engineering Institute, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0002-7338-1727
Jinseok HeoDepartments of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, and Medical Science and Engineering, POSTECH-CATHOLIC Biomedical Engineering Institute, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0009-0000-8401-3033
Hyunseo JeonDepartments of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, and Medical Science and Engineering, POSTECH-CATHOLIC Biomedical Engineering Institute, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.
Shiyang ChangDepartment of Histology and Embryology, Hebei Medical University, Shijiazhuang, China.
Wonseok ChoiDepartment of Biomedical Engineering and Medical Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0002-7239-1237
Chulhong KimDepartments of Convergence IT Engineering, Electrical Engineering, Mechanical Engineering, and Medical Science and Engineering, POSTECH-CATHOLIC Biomedical Engineering Institute, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0001-7249-1257
Zhifen YangDepartment of Obstetrics, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0003-1464-0140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The placenta is a pregnancy-specific organ, functioning as the maternal-fetal interface and mediating essential processes including exchange, protection, and endocrine regulation. Placental abnormalities contribute to the pathophysiology, onset, progression, and prognosis of major perinatal disorders, making imaging modalities that enable their detection and monitoring crucial. Ultrasound (US) imaging is the principal modality for placental imaging, providing structural assessment with B-mode and blood flow evaluation with Doppler mode. Furthermore, advanced techniques such as 3D power Doppler, quantitative US, and shear-wave elastography expand the capabilities of placental US imaging. Photoacoustic (PA) imaging enables observation of the optical properties of endogenous chromophores (e.g., hemoglobin) with high spatial resolution and measures blood oxygenation, a key factor in placental dysfunction, offering substantial value for placental imaging. In this review, we cover US/PA imaging techniques for placental imaging, including preclinical and clinical studies. In addition, by considering current limitations and potential solutions, we suggest future trajectories for the advancement of US/PA imaging in this field.

Indexed as

PlacentaPlacenta DiseasesAnimalsFemaleHumansPhotoacoustic TechniquesPregnancy

Identifiers

PMID41604485
PMCPMC12851039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.